New Genetic Approach Improves Huntington's Symptoms in Mice

A new study in Nature News by lead author Dr. Mark Detloff and his team shows that restoring cortical disinhibition in mice using a specific gene therapy improved symptoms of Huntington's disease. The gene editing technique, targeting cortical interneurons, reversed some of the neurodegenerative effects usually seen in the condition. This offers a potential new avenue for treating Huntington's.